Blockchain secures individual transactions with cryptography, creating a tamper-proof chain. In contrast, distributed ledger technologies cover various technologies that may not adhere strictly to blockchain's specific structure. We will start the book by defining blockchain elements, comparing it to DLT, exploring security mechanisms, and looking at Bitcoin's history, transactions, wallets, keys, mining, and forensics. Further in the book, we will explore Ethereum's evolution, Ethereum virtual machine, and smart contracts. We will also discover permissioned blockchains with Hyperledger Fabric and understand crypto assets, ERC20, ERC721 tokens, NFTs, and cryptocurrencies. With real-world examples and practical insights, you will gain a solid grasp of the fundamentals and practical applications that make blockchain a game-changer in various industries.