This Synopsis of Transfusion Medicine contains the advanced information for the Transfusion Specialists. The chapter of leucoreduction, Neonatal transfusion and massive transfusion is the need of hour for the day to provide safe and quality blood and Blood products to the patients. Massive transfusion is essential part of trauma medicine, where the road side accident victim need large volume of blood at short time. The accreditation and the current amendments in Drugs and Cosmetic Act will provide up to date information to the transfusion expert. Modern technology in reducing the window period in Transfusion transmitted infection in the chapter in this book will update the knowledge about these disease.